منابع مشابه
Simultaneous radioimmunoassay of thyrotropin and thyroxine in human serum.
The importance of early diagnois and treatment of congenital hypothyroidism has been well established, and several screening programs have been undertaken to detect neonates with this disorder by measurement of concentrations of thyrotropin or thyroxine in the serum. However, measurement of either hormone alone may fail to identify all affected patients. Accordingly, we have established a simul...
متن کاملDetermination of free thyroxine in serum by radioimmunoassay.
We describe a sensitive and specific radioimmunoassay for free thyroxine, directly determined in the diffusate obtained from equilibrium dialysis of serum. The intra- and interassay precisions were 7.5 +/- 0.27 and 9.1 +/- 0.58 ng/liter (mean +/- SD), respectively. The free thyroxine concentrations of normal persons and patients with thyroid disease were as follows: normal, 7.6 +/- 1.7; euthyro...
متن کاملRadioimmunoassay for human thyroxine-binding prealbumin.
A radioimmunoassay (RIA) for human thyroxine-binding prealbumin (PA) is described. It employs highly purified PA, anti-human PA serum at 1:30,000 final dilution, normal bovine serum as a carrier, and polyethyleneglycol to precipitate the immune complexes. This assay is extremely sensitive (limit of detection less than 0.2 micrograms per dL or less than 3.6 X 10(-15) moles per tube), accurate (r...
متن کاملAssessment of a method for measuring serum thyroxine by radioimmunoassay, with use of polyethylene glycol precipitation.
We assessed the efficacy of a new thyroxine radioimmunoassay kit (Abott) in which polyethylene glycol is used to separate bound from free hormone. Mean serum thyroxine was 88 +/- 15 (+/-SD) microgram/liter for 96 normal persons. Results for hypothyroid and hyperthyroid persons were clearly separated from those for normal individuals. Women taking oral contraceptive preparations showed variable ...
متن کاملComparison of eleven commercially available kits for the radioimmunoassay of serum thyroxine.
Zusammenfassung: Elf der in den Niederlanden kommerziell erhältlichen Testbestecks für den Radioimmunassay von Thyroxin wurden hinsichtlich Zuverlässigkeit, Empfindlichkeit und Einfachheit der Ausführung verglichen. Die Variationskoeffizienten in der Serie und von Tag zu Tag waren im Bereich von 4,6—11,3% und die Wiederfindung von zugesetztem Thyroxin betrug 85-114%. Hundert Ansätze können in 2...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1976
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.120.125